Paul R. Blakemore
Professor
Advisor
Department of Chemistry
Paul R. Blakemore
Professor
Advisor
Department of Chemistry
Research
Research within the Blakemore Research Group is focused on the development of new synthetic methods and concepts for the absolute control of molecular constitution and stereochemistry with an emphasis on connective stereospecific transformations.
Research Interests
Synthetic Organic Chemistry
Education
Ph.D., Chemistry, University of Glasgow, Glasgow, UK (1999).
B.Sc., Chemistry and Mathematics, University of Southampton, Southampton, UK (1995);
Publications
- "Synthesis of Thioalkynes by Desilylative Sonogashira Cross-Coupling of Aryl Iodides and 1-Methylthio-2- (trimethylsilyl)ethyne," Y. Cao, Y. Huang, and P. R. Blakemore* Eur. J. Org. Chem. 2022, e202200498.
- "Stereospecific Synthesis of Conjugated Dienes by Carbenoid Eliminative Cross-Coupling Using Lithiated Allylic Carbamates," S. D. Tanpure, P. R. Blakemore* Eur. J. Org. Chem. 2021, 4932-4937.
- "Total Synthesis of Chalaniline B: An Antibiotic Aminoxanthone from Vorinostat-Treated Fungus Chalara sp. 6661," M. Khoshbakht, B. Thanaussavadate, C. Zhu, Y. Cao, L. N. Zakharov, S. Loesgen, P. R. Blakemore* J. Org. Chem. 2021, 86, 7773-7780.
- "Synthesis of a P-Glycoprotein Inhibitor and Its High Energy (Z)-Isomer by Carbenoid Eliminative Cross-Coupling," S. D. Tanpure, M. F. El-Mansy, P. R. Blakemore* Org. Lett. 2020, 22, 2999-3003.
- "Formation of Olefins by Eliminative Dimerization and Eliminative Cross-Coupling of Carbenoids: A Stereochemical Exercise," P. R. Blakemore, R. W. Hoffmann Angew. Chem., Int. Ed. 2018, 57, 390-407.