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Paul Blakemore in front of black backdrop

Paul R. Blakemore

Professor
Department of Chemistry

Paul R. Blakemore

Professor
Department of Chemistry

Research

Research within the Blakemore Research Group is focused on the development of new synthetic methods and concepts for the absolute control of molecular constitution and stereochemistry with an emphasis on connective stereospecific transformations.

Research Interests

Synthetic Organic Chemistry

Education

Ph.D., Chemistry, University of Glasgow, Glasgow, UK (1999).

B.Sc., Chemistry and Mathematics, University of Southampton, Southampton, UK (1995);

Publications

  • "Synthesis of Thioalkynes by Desilylative Sonogashira Cross-Coupling of Aryl Iodides and 1-Methylthio-2- (trimethylsilyl)ethyne," Y. Cao, Y. Huang, and P. R. Blakemore* Eur. J. Org. Chem. 2022, e202200498.
  • "Stereospecific Synthesis of Conjugated Dienes by Carbenoid Eliminative Cross-Coupling Using Lithiated Allylic Carbamates," S. D. Tanpure, P. R. Blakemore* Eur. J. Org. Chem. 2021, 4932-4937.
  • "Total Synthesis of Chalaniline B: An Antibiotic Aminoxanthone from Vorinostat-Treated Fungus Chalara sp. 6661," M. Khoshbakht, B. Thanaussavadate, C. Zhu, Y. Cao, L. N. Zakharov, S. Loesgen, P. R. Blakemore* J. Org. Chem. 2021, 86, 7773-7780.
  • "Synthesis of a P-Glycoprotein Inhibitor and Its High Energy (Z)-Isomer by Carbenoid Eliminative Cross-Coupling," S. D. Tanpure, M. F. El-Mansy, P. R. Blakemore* Org. Lett. 2020, 22, 2999-3003.
  • "Formation of Olefins by Eliminative Dimerization and Eliminative Cross-Coupling of Carbenoids: A Stereochemical Exercise," P. R. Blakemore, R. W. Hoffmann Angew. Chem., Int. Ed. 2018, 57, 390-407.