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Douglas F Barofsky

Emeritus Professor
Department of Chemistry

Douglas F Barofsky

Emeritus Professor
Department of Chemistry

General interests encompass the investigation and development of ionization processes, methodologies, and instrumentation employed in mass spectrometry and the application of mass spectrometry to the elucidation of structural features that govern the functions of biological molecules and to the analysis of organic molecules found in environmental matrices. Individual studies entail development of tandem time-of-flight mass spectrometry (TOF MS/MS); development of electron capture ionization time-of-flight mass spectrometry (ECI TOF MS); investigation of electron capture dissociation of peptides and proteins; proteomics based on protein-function; investigation of protein/nucleic acid interaction; and environmental analysis of fluorinated alkyl substances.


Post-Doctoral Associate, (1968-69), University of Bonn, West Germany

Post-Doctoral Associate, (1967-68), Department of Physics, Pennsylvania State University

Ph.D. (1967), Physics, Pennsylvania State University

M.S. (1965), Physics, Pennsylvania State University

B.S. (1963), Physics, Washington State University

Associate of Arts (1961) Clark College, Washington


  • Semivolatile Fluorinated Organic Compounds in Asian and Western U.S. Air Masses, Environ. Sci. Technol., 2007, 41 (24), 8248-8255.
  • Charge-Remote Metastable Ion Decomposition of Free Fatty Acids under FAB MS: Evidence for Biradical Ion Structures, Anal. Chem., 2007, 79 (7), 2822-2826.
  • Distinguishing between Cis/Trans Isomers of Monounsaturated Fatty Acids by FAB MS, Anal. Chem., 2007, 79 (4), 1519-1522.
  • Fluorochemical Mass Flows in a Municipal Wastewater Treatment Facility, Environ. Sci. Technol., 2006, 40 (23), 7350-7357.
  • Resonant Electron Capture by Some Amino Acids and Their Methyl Esters, J. Am. Chem. Soc., 2006 128 (16), 5506-5515.


  • Alexander von Humboldt-Stiftung Senior Researcher Fellowship, University of Bonn, West Germany (1982)
  • Phi Theta Kappa Academic Honorary (1969)
  • Alexander von Humboldt-Stiftung Fellowship, University of Bonn, West Germany (1968)