Publications

• Geller, B.L., Li, L., Martinez, F., Sully, E., Sturge, C.R., Dalyt S.M., Pybus, C., and Greenberg, D.E. 2018. Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella penumoniae. J. Antimicrob. Chemother. Mar 1. PMID 29506074.
• Daly, S.M., Sturge, C.R., Marshall-Batty, K.R., Felder-Scott, C.F., Jain, R., Geller, B.L., and Greenberg, D.E. 2018. Antisense inhibitors retain activity in pulmonary models of Burkholderia infection. ACS Infect. Dis. Mar 1. PMID 29461800.
• Daly, S.M., Sturge, C.R., Felder-Scott, C.F., Geller, B.L., and Greenberg, D.E. 2017. MCR-1 inhibition with peptide-conjugated phosphorodiamidate morpholino oligomers restores sensitivity to polymyxin in Escherichia coli. MBio. 8(6): pii:e01315-17. doi: 10.1128/mBio.01315-17.
• Howard, J.J., Sturge, C.R., Moustafa, D.A., Daly, S.M., Marshall-Batty, K.R., Felder, C.F., Zamora, D., Yabe-Gill, M., Labandeira-Rey, M., Bailey, S.M., Wong, M., Goldberg, J.B., Geller, B.L., and Greenberg, D.E. 2017. Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob. Agents Chemother. Jan 30. pii: AAC.01938-16. doi: 10.1128/AAC.01938-16. [Epub ahead of print] PMID: 28137807
• Otsuka, T., Brauer, A.L., Kirkham, C., Sully, E.K., Pettigrew, M.M., Kong, Y., Geller, B.L., and Murphy, T.F. 2017. Antimicrobial activity of antisense peptide-peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms. J. Antimicrob. Chemother. 72(1):137-144.
Sully, E.K., Geller, B.L., Li, L., Moody, C.M., Bailey, S.M., Moore, A.L., Wong, M., Nordmann, P., Daly, S.M., Sturge, C.R., Greenberg, D.E. 2016. Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo. J. Antimicrob Chemother. pii: dkw476. doi: 10.1093/jac/dkw476. [Epub ahead of print] PMID: 27999041; http://www.kgw.com/news/health/oregon-state-professor-discovers-molecule-to-fight-antibiotic-resistant-bacteria/393736223.
Sully, E.K. and Geller, B.L. 2016. Antisense antimicrobial therapeutics. Curr. Opin. Microbiol. 33:47-55.
Greenberg, D.E., Sturdevant, D.E., Marshall-Batty, K.R., Chu, J., Pettinato, A.M., Virtaneva, K., Lane, J., Geller, B.L., Porcella, S.F., Gallin, J.I., Holland, S.M., and Zarember, K.A. 2015. Simultaneous host-pathogen transcriptome analysis during Granulibacter bethesdensis infection of neutrophils from healthy subjects and patients with chronic granulomatous disease. Infect. Immun. 83(11):4277-92.
Geller, B.L., and Greenberg, D.E. 2014. Peptide-conjugated Phosphorodiamidate Morpholino Oligomers: A New Strategy for Tackling Antibiotic Resistance. Ther. Deliv. 5(3): 243-5.
Geller, B.L., Marshall-Batty, K., Schnell, F.J., McKnight, M.M., Iversen, P.L., and Greenberg, D.E. 2013. Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth in vitro and in vivo. J. Infect. Dis.
Reese, K.A., Lupfer, C., Johnson, R.C.Mitev, G.M., Mullen, V.M., Geller, B.L., and Pastey, M. 2013. A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza Virus Prolongs Survival of Vaccinated Chickens. Vet. Med. Intl. Article 316926.
Puckett, S.E., K.A. Reese, G.M. Mitev, V. Mullen, R.C. Johnson, K.R. Pomraning, B.L. Mellbye, L.D. Tilley, P.L. Iversen, M. Freitag and B.L. Geller. 2012. Bacterial Resistance to Antisense Peptide-Phosphorodiamidate Morpholino Oligomers. Antimicrob. Agents Chemother. 56:6147-6153.
Panchal, R.G., B.L. Geller, B. Mellbye, D. Lane, P.L. Iversen and S. Bavari. 2012. Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis. Nuc. Acid Therap. 22:305-311.
Greenberg, D. E., K. R. Marshall-Batty, L. R. Brinster, K. A. Zarember, P. A. Shaw, B. L. Mellbye, P. L. Iversen, S. M. Holland, and B. L. Geller. 2010. Antisense Phosphorodiamidate Morpholino Oligomers Targeted to an Essential Gene Inhibit Burkholderia cepacia complex. J. Infect. Dis., 201(12):1822-30.
Mellbye, B. L., D. D. Weller, J. N. Hassinger, M. D. Reeves, C. E. Lovejoy, P. L. Iversen, and B. L. Geller. 2010. Cationic Phosphorodiamidate Morpholino Oligomers Efficiently Prevent Growth of Escherichia coli in vitro and in vivo. J. Antimicrob. Chemother. 65:98-106.
Mitev, G. M., B. L. Mellbye, P. L. Iversen, and B. L. Geller. 2009. Inhibition of Intracellular Growth of Salmonella enterica serovar 1 typhimurium in Tissue. Antimicrob. Agents Chemother. 53:3700-3704.
Shen, N., J. Ko, G. Xiao, D. Wesolowski, G. Shan, B. Geller, M. Izadjoo, and S. Altman. 2009. Inactivation of Expression of Several Genes in a Variety of Bacterial Species by EGS Technology. Proc. Natl. Acad. Sci. U.S.A. 106:8163-8168.
Mellbye, B. L., S. E. Puckett, L. D. Tilley, P. L. Iversen, and B. L. Geller. 2009. Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency Against Escherichia coli in vitro and in vivo. Antimicrob. Agents Chemother. 53:525-530.
Tilley, L., B. Mellbye, S. E. Puckett, P. L. Iversen, and B. L. Geller. 2007. Antisense Phosphorodiamidate Morpholino Oligomer-Peptide Conjugate: Dose-Response in Mice Infected with Escherichia coli. J. Antimicrob. Chemother. 59:66-73.
Tilley, L., O.S. Hine, J.A. Kellogg, J.N. Hassinger, D. Weller, P.L. Iversen, and B.L. Geller. 2006. Gene-Specific Effects of Antisense Phosphorodiamidate Morpholino Oligomer-Peptide Conjugates on Escherichia coli and Salmonella typhimurium in Pure Culture and in Tissue Culture. Antimicrob, Agents Chemother. 50: 2789-2796.
Geller, B.L., J. Deere, L. Tilley, and P.L. Iversen. 2005. Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis. J. Antimicrob. Chemother. 55:983-988.
Deere, J., P. Iversen, and B.L. Geller. 2005 Antisense phosphorodiamidate morpholino oligomer length and target position effect on gene-specific inhibition in Escherichia coli. Antimicrob. Agents Chemother. 49:249-255.
Geller, B.L., J.D. Deere, D.A. Stein, A.D. Kroeker, H.M. Moulton, and P.L. Iversen. 2003. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers. Antimicrob. Agents Chemother. 47:3233-3239.